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Comparison of the effects of bispectral index-controlled use of remifentanil on propofol consumption and patient comfort in patients undergoing colonoscopy

Journal Volume 78 - 2015
Issue Fasc.3 - Original articles
Author(s) Murat Bilgi, Umit Yasar Tekelioglu, Mustafa Sit, Abdullah Demirhan, Akcan Akkaya, Isa Yildiz, Hasan Kocoglu
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(1) Department of Anesthesiology and Reanimation, (2) Department of general surgery, Abant Izzet Baysal University Medical School, Bolu, Turkey.

Background and study aims : In endoscopic procedures, propofol can be safely administered either alone or in conjunction with remifentanil. The aim of the study is to compare the effects of the administration of propofol alone and the administration of remifentanil in addition to propofol on patient and endoscopist satisfaction, preoperative hemodynamic response, and propofol consumption. Materials and methods : A totally 60 patients were enrolled in the study. Propofol group (Group 1) : A 0.4-mg/kg propofol bolus and 1 mg/kg/h maintenance infusion of propofol until a bispectral Index value of 70-75 was achieved. Propofol + remifentanil group (Group 2) received a 0.4 mg/kg propofol bolus dose and maintained with a 0.5 mg/kg/h infusion of propofol + 0.2 mcg/kg/min infusion of remifentanil. The infusion dose of remifentanil was maintained, and the propofol infusion dose was titrated until a BIS value of 70- 75 was achieved.

© Acta Gastro-Enterologica Belgica.
PMID 26448413